Vernon Justice Ebegboni

The paper identifies a core regulatory circuit in rhabdomyosarcoma and shows that targeting two co-activators synergistically inhibits tumor growth.

This study shows that EWSR1 forms a ribonucleoprotein network with nascent RNA, and its loss leads to compensatory reorganization of FUS and TAF15, revealing functional redundancy in maintaining nascent RNA homeostasis.

This study identifies HNRNPH1-regulated splicing events affecting EIF4G1 transcript variants and AURKA 5' UTR structure, influencing protein expression and function.

This study identifies ETS1 as a target of the EWSR1::FLI1 fusion oncoprotein in Ewing sarcoma, showing it regulates TNS3 expression, which promotes cell movement and is linked to metastasis.