Cancer BiologyBlood Cancer DiscoveryPeer-reviewed
Selective Enhancer Dependencies in MYC-Intact and MYC-Rearranged Germinal Center B-cell Diffuse Large B-cell Lymphoma
Ashwin R. Iyer, Aishwarya Gurumurthy, Alec Chu…·Russell J.H. Ryan
The paper identifies enhancer dependencies in MYC-intact and MYC-rearranged GCB-DLBCL using CRISPRi screens, revealing distinct regulatory mechanisms.