GeneticsbioRxivPreprint
Pus7 mutation links tRNA dysregulation to aggressive behavior through activation of the integrated stress response and glycolytic reprogramming
Michael Stock, Maria Guillen-Angel, Monika Witzenberger…·Jean‐Yves Roignant
The paper shows that Pus7 mutations reduce tRNA-Asp levels, activating the integrated stress response and glycolytic reprogramming, which contributes to aggressive behavior.
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