Author

Karin C. Nitiss

University of Illinois ChicagoORCID 0000-0002-3548-5090Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:DNA methylation· 1 Organism:human· 1 Research Focus:protein design· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

John L. NitissiD· 2 shared Yilun SuniD· 2 shared Anna T. Rogojina· 1 shared Hannah N. MilesiD· 1 shared James M. BergeriD· 1 shared Lisa M. Miller JenkinsiD· 1 shared Matthew A. Gilbertson· 1 shared Nicole StantialiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

John L. NitissORCID

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2 papers

Recent·Most cited

Molecular BiologyScience AdvancesPeer-reviewedNov 13, 2020

A conserved SUMO-Ubiquitin pathway directed by RNF4/SLX5-SLX8 and PIAS4/SIZ1 drives proteasomal degradation of topoisomerase DNA-protein crosslinks

Yilun Sun, Lisa M. Miller Jenkins, Yijun P. Su…·Yves G. Pommier

The paper identifies a conserved SUMO-Ubiquitin pathway involving PIAS4 and RNF4 that mediates proteasomal degradation of topoisomerase DNA-protein crosslinks in human and yeast cells.

149 citationstop 2%

humanyeast

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedOct 12, 2020

Trapped Topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast

Nicole Stantial, Anna T. Rogojina, Matthew A. Gilbertson…·John L. Nitiss

This study identifies a yeast Top2 mutant that generates stabilized cleavage intermediates, leading to de novo duplications via nonhomologous end-joining.

29 citations

yeastDNA methylation

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