Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Trapped Topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast
Nicole Stantial, Anna T. Rogojina, Matthew A. Gilbertson…·John L. Nitiss
This study identifies a yeast Top2 mutant that generates stabilized cleavage intermediates, leading to de novo duplications via nonhomologous end-joining.
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