Cancer BiologyNature CommunicationsPeer-reviewed
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity
Shuwei Liang, Eric Tran, Xin Du…·Tony Tiganis
This study shows that a PTP1B/PTPN2 inhibitor enhances T cell anti-tumor immunity in mice, improves tumor response to PD1 therapy, and avoids immune-related toxicities.
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