Author
Dennis Kappei
National University of SingaporeORCID 0000-0002-3582-2253Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 14 mutual co-author links5 papers
Recent·Most cited
- Cancer BiologyOncogenePeer-reviewed
Wnt target IQGAP3 promotes Wnt signaling via disrupting Axin1-CK1α interaction.
Muhammad Bakhait Bin Rahmat, Aashiq Hussain, Yu Xuan Teh…·Yoshiaki Ito
This study identifies IQGAP3 as a Wnt signaling mediator that stabilizes β-catenin by disrupting Axin1-CK1α interaction and is itself regulated by Wnt signaling.
4 citations - Cancer BiologybioRxivPreprint
Genotoxic chemotherapy impedes complement dependent cytotoxicity via Chk1-mediated CD59 regulation
Allison S. Y. Chan, Akshaya Anbuselvan, Patrick William Jaynes…·Anand Devaprasath D. Jeyasekharan
This study shows genotoxic chemotherapy increases CD59 expression, reducing complement-dependent cytotoxicity and rituximab efficacy in DLBCL via Chk1-mediated regulation.
DOI 10.1101/2025.02.17.638751 - Cell BiologybioRxivPreprint
The TARZN complex binds de novo enhancer mutations and promotes oncogenic expression in T-ALL
Nurkaiyisah Zaal Anuar, Chai Yeen Goh, Boon Haow Chua…·Dennis Kappei
The paper identifies the TARZN complex, which binds de novo enhancer mutations and promotes TAL1 overexpression in T-ALL through RNA methylation.
DOI 10.1101/2025.01.24.634708 - GeneticsbioRxivPreprint
Formation and recycling of an active epigenetic mark mediated by cell cycle-specific RNAs
Alexander K. Ebralidze, Simone Ummarino, Mahmoud Adel Bassal…·Daniel Geoffrey Tenen
The paper shows that cell cycle-specific long noncoding RNAs regulate the establishment and recycling of the acetylated histone H2A.Z epigenetic mark.