Author

Heiko Düßmann

Royal College of Surgeons in IrelandORCID 0000-0002-3582-8057Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Jochen H.M. PrehniD· 4 shared Batuhan KısakoliD· 3 shared Anna SturrockiD· 2 shared Daniel B. LongleyiD· 2 shared Emir BozkurtiD· 2 shared Fiona GintyiD· 2 shared John Patrick BurkeiD· 2 shared Mohammadreza AzimiiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersCancer Biology

Jochen H.M. PrehnORCID

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4 papers

Recent·Most cited

Cancer BiologyCell Death and DifferentiationPeer-reviewedJun 30, 2026

Cell engulfment defines spatially distinct competitive metabolic niches associated with clinical outcomes in colorectal cancer

Emir Bozkurt, Batuhan Kısakol, Heiko Düßmann…·Jochen H.M. Prehn

The paper investigates cell engulfment in colorectal cancer, showing it creates competitive metabolic niches linked to clinical outcomes.

1 citation

humanspatial transcriptomics

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BioinformaticsbioRxivPreprintNov 24, 2025

A multi-step filtering pipeline for human read removal enhances detection of Fusobacterium in WGS datasets with immunohistochemical confirmation in mucinous rectal cancer.

Mariia S. Frolova, Barry Maguire, Heiko Düßmann…·Jochen H.M. Prehn

The paper introduces a multi-step filtering pipeline to remove human reads from WGS data, improving detection of Fusobacterium in rectal cancer samples confirmed by immunohistochemistry.

DOI 10.1101/2025.11.24.690231

humanwhole-genome sequencing

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Cancer BiologybioRxivPreprintNov 20, 2025

Humanized glioblastoma patient-derived orthotopic xenografts recreate a locally immunosuppressed human immune ecosystem amenable to immunotherapeutic modulation

Pilar M. Moreno‐Sanchez, Anaïs Oudin, Batuhan Kısakol…·Anna Golebiewska

This study develops humanized glioblastoma PDOX models to study tumor-immune interactions and test immunotherapies in a human context.

1 citation

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Cancer BiologyThe Journal of PathologyPeer-reviewedAug 2, 2024

Spatial Effects of Infiltrating T cells on Neighbouring Cancer Cells and Prognosis in Stage III CRC patients

Mohammadreza Azimi, Sanghee Cho, Emir Bozkurt…·Jochen H.M. Prehn

The paper investigates the spatial relationship between T cells and cancer cells in stage III CRC patients, finding that closer proximity of T cells to cancer cells is associated with better disease-free survival.

8 citations

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