Molecular BiologybioRxivPreprint
C. difficile-associated antibiotics prime the host for infection by a microbiome-independent mechanism.
Jemila C. Kester, Douglas K. Brubaker, Jason G. Velazquez…·Linda Gay Griffith
This study shows that certain antibiotics increase CDAD risk through host-driven changes, not just microbiome disruption, by impairing mucosal barriers and immune function in human gut models.
DOI 10.1101/728170