Valérie Najburg

This paper modifies a measles vaccine by removing a viral protein to create a cancer immunotherapy that activates the immune system via RIG-I signaling, leading to tumor regression in multiple models.

sgDI-tector detects and quantifies subgenomic RNAs in SARS-CoV-2 NGS data, identifying a ranked set of sgRNAs and comparing their levels to defective interfering viral genomes.

This study identifies Zea, an RNA-binding protein secreted by L. monocytogenes, which stabilizes bacterial RNAs and activates RIG-I signaling to enhance interferon β production and modulate virulence.