Haley A. Hardtke

The paper tests the one-receptor, one-JAK model by measuring JAK1 and TYK2 interactions with receptor ICDs, finding graded and cross-reactive binding rather than exclusive, constitutive interactions.

The paper defines the minimal sequence requirements of RNA polymerase II CTD across transcriptional stages using structural analysis and synthetic constructs, revealing a 'zipper' model for PIC assembly and transcription progression.

This study identifies HAF2 as a histone acetyltransferase that interacts with EIN2-C and PDC to regulate H3K14ac and H3K23ac in response to ethylene.

The paper develops a method to detect combinatorial phosphorylation patterns on RNA polymerase II CTD and shows they recruit TREX for mRNA processing and export.