Author

Nam Y. Lee

University of ArizonaORCID 0000-0002-3730-0774Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Karthikeyan MythreyeiD· 3 shared Nadine HempeliD· 3 shared Asha KumariiD· 2 shared Rébécca PhaëtoniD· 2 shared Abhyudai SinghiD· 1 shared Ahmed Emam AbdelnabyiD· 1 shared Alex S ChoiiD· 1 shared Amal Taher ElhawiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCancer Biology

Karthikeyan MythreyeORCID

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3 papers

Recent·Most cited

Cancer BiologyJCI InsightPeer-reviewedJan 15, 2026

Anoikis resistance and metastasis of ovarian cancer can be overcome by CDK8/19 Mediator kinase inhibition.

Mehri Monavarian, Resha Rajkarnikar, Emily Faith Page…·Karthikeyan Mythreye

This study shows CDK8/19 inhibition can reverse anoikis resistance and metastasis in ovarian cancer by altering transcriptional programs.

5 citationstop 1%

humanbulk RNA-seq

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Cancer BiologyEMBO ReportsPeer-reviewedAug 27, 2024

Alternative splice variants of the mitochondrial fission protein DNM1L/Drp1 regulate mitochondrial dynamics and cell fate in ovarian cancer.

Zaineb Javed, Dong Hui Shin, Weihua Pan…·Nadine Hempel

This study identifies an alternative splice variant of Drp1 in ovarian cancer that promotes metastasis and chemoresistance by altering mitochondrial dynamics.

34 citationstop 5%

humanexperimental assay

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BiochemistryCell Communication and SignalingPeer-reviewedFeb 15, 2024

Heparan sulfate modifications of betaglycan promote TIMP3-dependent ectodomain shedding to fine-tune TGF-β signaling.

Alex S Choi, Laura M. Jenkins, Wade C. Barton…·Karthikeyan Mythreye

This study identifies heparan sulfate modifications as critical for betaglycan ectodomain shedding, which regulates TGF-β signaling and has clinical implications in ovarian cancer.

7 citations

humanexperimental assay

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