NeuroscienceNature CommunicationsPeer-reviewed
Structural Basis for pH-Gating of the K+ Channel TWIK1 at the Selectivity Filter
Toby S. Turney, Vivian Li, Stephen Graf Brohawn
This study presents cryo-EM structures of TWIK1 at different pH levels, revealing how protonation of an extracellular histidine triggers conformational changes that gate the K+ channel.
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