Pascal Lafrenz

The paper benchmarks DNA methylation sequencing workflows against an experimental gold-standard, identifying superior workflows and developing a sustainable benchmarking platform.

This paper introduces a new ribosome profiling protocol that is faster, cheaper, and more sensitive, enabling use with minimal RNA input.

This study identifies miR-2954 as a male-essential microRNA critical for avian sex chromosome dosage compensation, showing its role in balancing gene expression in males and females.

The paper introduces COSMOS+ to integrate mechanistic prior knowledge with multi-omics data analysis to generate mechanistic hypotheses about disease resistance mechanisms.