Author

Thomas Guillard

Centre Hospitalier Universitaire de ReimsORCID 0000-0002-3795-0398Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Agnès Ferroni· 1 shared Anaëlle MuggeoiD· 1 shared Anne Doléans-JordheimiD· 1 shared Arnaud BonnometiD· 1 shared Aya Ghassani· 1 shared Cléophée Van Maele· 1 shared Émilie Cardot-MartiniD· 1 shared Emilie LuczkaiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMicrobiology

Agnès Ferroni

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewedDec 11, 2023

Mutations in genes lpxL1, bamA and pmrB impair the susceptibility of cystic fibrosis strains of Pseudomonas aeruginosa to murepavadin

Aya Ghassani, Pauline Triponney, Maxime Bour…·Patricia Mariani‐Kurkdjian

The paper assesses murepavadin's activity against CF-related P. aeruginosa strains and identifies mutations in lpxL1, bamA, and pmrB that increase resistance.

10 citations

humanwhole-genome sequencing

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MicrobiologybioRxivPreprintOct 19, 2023

The panC-encoded pantothenate synthetase to tackle carbapenem-resistant OprD Pseudomonas aeruginosa mutant revealed through Tn-Seq

Cléophée Van Maele, Ségolène Caboche, Marin Moutel…·Thomas Guillard

This study identifies panC as a therapeutic target in OprD-deficient Pseudomonas aeruginosa by showing its role in growth and virulence through transposon sequencing and CRISPRi.

DOI 10.1101/2023.10.19.563089

bacteria (other)experimental assay

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