Developmental BiologyThe Journal of General PhysiologyPeer-reviewed
The TMEM16A Channel Mediates the fast polyspermy block in Xenopus Laevis
Katherine L. Wozniak, Wesley A. Phelps, Maiwase Tembo…·Anne E. Carlson
The paper identifies TMEM16A as the Ca2+-activated Cl- channel responsible for the fast block to polyspermy in Xenopus laevis eggs by showing that its inhibition reduces fertilization-evoked depolarization.
49 citations