Jordana T. Bell

The paper identifies variance QTLs (vQTLs) and gene-environment interactions for body fat distribution using UK Biobank MRI and genetic data, with replication in external cohorts.

The paper introduces methbiome, a tool for reference-based DNA methylation profiling of long-read metagenomic data, enabling cross-platform and between-sample comparison of methylation signals in microbiomes.

The paper identifies vmeQTLs for blood DNA methylation variance in MZ twins, showing gene-environment interactions and cell-type effects relevant to immune disease.

This study identifies genetic loci regulating fatty acid levels in adipose tissue and links them to metabolic and cardiovascular traits.

The paper finds that higher serum theobromine levels are associated with slower epigenetic ageing in humans, as measured by GrimAge and DNAmTL.

The paper identifies a locus, SH3BP4, where DNA methylation correlates with mtDNAq and obesity-related traits in adipose tissue, suggesting potential causal relationships.

The paper identifies DNA methylation and gene expression changes in human blood after a meal, linking them to cardiometabolic health and obesity-related genes.

This paper compares methods for detecting genetic variants affecting phenotypic variance under gene-environment interactions and identifies optimal approaches for different exposure types.

The paper identifies genetic impacts on DNA methylation across 724,499 CpGs in blood samples, revealing co-localisations with disease traits and regulatory mechanisms.

This study investigates how hemin availability affects DNA methylation and gene expression in Porphyromonas gingivalis, identifying coordinated changes in six genes related to virulence.

This study identifies DNA methylation changes associated with extreme obesity and finds causal effects on obesity and metabolic disturbances using Mendelian Randomisation.

This study shows that age-related skewed X chromosome inactivation in females is linked to increased cardiovascular disease risk and cancer incidence.

The paper examines the association between adipose tissue ACE2 expression and cardio-metabolic risk factors, finding lower ACE2 levels linked to T2D, obesity, and inflammation-related cell type changes.

This study maps DNA methylation changes across the human life course using data from 7,037 individuals, showing increased variability and age-related mean changes at specific CpG sites.

The paper identifies differentially methylated regions and methylation QTLs associated with teen depression and early puberty using longitudinal DNA methylation data from the Fragile Families Child Wellbeing Study.

This study identifies DNA methylation sites associated with coffee and tea consumption using EWAS, finding potential links to fatty liver disease through PHGDH expression.

The paper identifies age-related DNA hypermethylation at specific human tRNA gene loci using DNA methylome data from peripheral blood.

The paper identifies 31 host genetic loci influencing gut microbiome composition through GWAS and suggests causal effects in inflammatory diseases.

This study identifies 137 genome-wide significant loci associated with DNA methylation biomarkers of ageing using DNAm and SNP data from over 41,000 individuals.

This study quantifies XCI skewing in female twins across tissues, showing age- and tissue-specific heritability and associations with smoking in older females.

This study identifies nine novel DNA methylation sites associated with fasting glucose and insulin levels by integrating cross-omics data from multiple cohorts.

This study identifies DNA methylation changes in blood and tissue samples associated with periodontal disease in older female twins.

This study identifies smoking-associated DNA methylation and gene expression changes in adipose tissue and links some to cardio-metabolic health outcomes.

The paper identifies a differentially variable DNA methylation signature in rheumatoid arthritis discordant monozygotic twins, suggesting epigenetic variability contributes to autoimmune disease.

This study identifies 4 new risk loci for cannabis use through GWAS, finds genetic overlap with mental health, and shows a causal link between schizophrenia and cannabis use.

The paper quantifies age-related changes in gene expression levels, splicing, and variance across tissues and identifies environmental and genetic influences on these changes in a twin cohort.

This study identifies genetic variants associated with epigenetic age acceleration and shows TERT's role in regulating the DNA methylation clock.