Amr H. Sawalha

The paper quantifies genetic determinants of ACE2 and TMPRSS2 expression across populations and finds lower expression in African populations, suggesting potential genetic factors influencing SARS-CoV-2 susceptibility.

The paper identifies a risk locus in IL6 that represses GPNMB via chromatin looping and MEF2-HDAC complex recruitment, linking it to disease susceptibility and immune responses.

The paper identifies novel transcripts and extensive allelic imbalance in the human MHC region using targeted capture sequencing and transcriptome alignment.