Author

Tatsuya Kobayashi

Harvard UniversityORCID 0000-0002-3889-5765Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Aya MatsuiiD· 2 shared Dan Gabriel DudaiD· 2 shared Peigen HuangiD· 2 shared Pin‐Ji LeiiD· 2 shared Tomofumi AndoiD· 2 shared Chengzhan ZhuiD· 1 shared Dandan YuaniD· 1 shared Hiroto KikuchiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Aya MatsuiORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedDec 8, 2025

Inhibiting B-cell-mediated Immunosuppression to Enhance the Immunotherapy Efficacy in Hepatocellular Carcinoma

Xin Liu, Zelong Liu, Chengzhan Zhu…·Dan Gabriel Duda

This study shows that B-cell depletion or TIM-1 targeting enhances immunotherapy efficacy in HCC by reducing B-cell-mediated immunosuppression and improving antigen presentation.

7 citations

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologyCancer Immunology ResearchPeer-reviewedNov 8, 2024

Combined blockade of CXCR4 and PD-1 enhances intratumoral dendritic cell activation and immune responses against HCC

Satoru Morita, Pin‐Ji Lei, Kohei Shigeta…·Dan Gabriel Duda

This study shows that blocking CXCR4 and PD-1 together improves dendritic cell activation and immune responses against HCC in mouse models.

31 citationstop 3%

mousebulk RNA-seq

𝕏 PostBluesky