Samantha L. Avina

This study shows that Cdc50, a lipid flippase regulatory subunit in Cryptococcus neoformans, controls membrane lipid homeostasis, extracellular vesicle biogenesis, and macrophage interactions, with loss of Cdc50 increasing phagocytosis and susceptibility to macrophage killing.

This study identifies Cig1 as an immunogenic antigen in a heat-killed Cryptococcus neoformans vaccine model, showing its role in T cell recruitment and cytokine production.