Pavel A. Makhnovskii

This study examines how 3-week disuse affects calf and thigh muscle phenotype and gene expression, finding greater declines in calf muscles with specific proteomic and transcriptomic changes.

This study examines how low-intensity neuromuscular electrical stimulation affects gene expression and muscle phenotype during one week of disuse, showing mixed benefits depending on muscle type.

The paper identifies transcription factors regulating gene expression in human soleus and vastus lateralis muscles before and after disuse, finding distinct responses and associations with inflammation and mitochondrial metabolism.

This study shows that knocking out six Hsp70 genes in Drosophila reduces locomotor speed and disrupts adaptation to exercise training, with changes in leg muscle gene expression.