Author

Giang T. Ong

Nanostring Technologies (United States)ORCID 0000-0002-3946-1627Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Dwayne L. Dunaway· 2 shared Yan LiangiD· 2 shared Alecksandr J. Kutchma· 1 shared Alyssa B. RosenbloomiD· 1 shared Andrew Klock· 1 shared Aster Wardhani· 1 shared Bonita J. BreweriD· 1 shared Carl Brown· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Dwayne L. Dunaway

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3 papers

Recent·Most cited

GeneticsPLoS GeneticsPeer-reviewedAug 20, 2026

Telomeric amplicons of SUL1 and Y' in yeast are generated by microhomology-mediated break induced replication occurring in cis

Bonita J. Brewer, Rebecca Martin, Elizabeth R. Ramage…·M. K. Raghuraman

The paper identifies a mechanism of gene amplification in yeast involving microhomology-mediated break-induced replication (mmBIR) at telomeres, leading to tandem duplication of chromosomal ends.

DOI 10.1371/journal.pgen.1012214

yeastDNA methylation

𝕏 PostBluesky

GenomicsbioRxivPreprintNov 3, 2021

High-plex Multiomic Analysis in FFPE at Subcellular Level by Spatial Molecular Imaging

Shanshan He, Ruchir Bhatt, Carl Brown…·Joseph Beechem

An automated in-situ imaging platform reads 980 RNAs and 108 proteins in FFPE tissue at subcellular resolution, with 0.0092 false calls per cell; 800,000-plus cells released publicly.

72 citations

humanspatial transcriptomics

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PathologybioRxivPreprintFeb 26, 2019

High multiplex, digital spatial profiling of proteins and RNA in fixed tissue using genomic detection methods

Christopher R. Merritt, Giang T. Ong, Sarah Church…·Joseph M. Beechem

This paper introduces Digital Spatial Profiling (DSP), a method for high-plex spatial analysis of proteins and RNA in tissue, and demonstrates its application in studying immune and cancer microenvironments.

DOI 10.1101/559021

humanprotein structure

𝕏 PostBluesky