Author

Adriaan Vanderstichele

Universitair Ziekenhuis LeuvenORCID 0000-0002-3984-2948Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:whole-genome sequencing· 2 Research Focus:batch correction / integration· 1 Organism:human· 1 Approach:optimal transport· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

An CoosemansiD· 2 shared Diether LambrechtsiD· 2 shared Dirk TimmermaniD· 2 shared Joris Robert VermeeschiD· 2 shared Tatjana JatsenkoiD· 2 shared Agnieszka WoźniakiD· 1 shared Antoine PassemiersiD· 1 shared Antonia Carla TestaiD· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBioinformatics

An CoosemansORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 4, 2024

Alleviating cell-free DNA sequencing biases with optimal transport

Antoine Passemiers, Tatjana Jatsenko, Adriaan Vanderstichele…·Yves Moreau

This paper introduces an optimal transport-based domain adaptation method to correct technical biases in cfDNA sequencing data, improving cancer detection and enabling cohort integration.

DOI 10.1101/2024.04.04.588204

whole-genome sequencingoptimal transport

𝕏 PostBluesky

Genetic & Genomic MedicineClinical ChemistryPeer-reviewedJun 29, 2022

Pan-cancer detection and typing by mining patterns in large genome-wide cell-free DNA sequencing datasets

Huiwen Che, Tatjana Jatsenko, Liesbeth Lenaerts…·Joris Robert Vermeesch

The paper develops a method to detect and type cancer using cfDNA sequencing data, achieving 81.62% accuracy in distinguishing malignant from control samples.

20 citations

humanwhole-genome sequencing

𝕏 PostBluesky