Tahmina Hossain

This study challenges the idea that antibiotic persisters are metabolically dormant by showing that Escherichia coli persisters remain metabolically active and exhibit dynamic gene expression changes.

The paper shows that Escherichia coli cells can enter a stress-prepared state that persists for generations but is lost upon dilution, indicating a transient, reversible cellular memory rather than genetic mutation.

This study examines antibiotic tolerance, persistence, and resistance in the minimal cell Mycoplasma mycoides JCVI-Syn3B, finding it rapidly evolves resistance and exhibits tolerance and persistence against multiple antibiotics.

This study identifies a complex transcriptional response in E. coli under lethal ampicillin concentrations, showing specific regulatory proteins drive coordinated gene expression changes.