GeneticsbioRxivPreprint
Polynucleotide Phosphorylase Stops Replication Restart by Degrading the RNA within R-loops during Replication-Transcription Conflicts
Oyku Sensoy, Juan Carvajal-Garcia, Shahin Boumi, Houra Merrikh
The paper shows that PNPase degrades RNA in R-loops to prevent replication restart and reduce mutations during replication-transcription conflicts.
DOI 10.64898/2026.06.02.729377