Mervin M. Fansler

The paper identifies the FXR1 network as a cytoplasmic mRNA scaffold that facilitates actomyosin remodeling by organizing signaling interactions.

The paper shows that subcytoplasmic mRNA localization affects protein output by determining mRNA and protein abundance through compartment-specific translation environments.

The paper benchmarks eight tools for identifying and quantifying alternative polyadenylation sites from RNA-seq data using real, synthetic, and 3'-end sequencing data.

The paper annotates 3'UTR cleavage sites in primary human and mouse cells and introduces scUTRquant to quantify 3'UTR isoform expression from scRNA-seq data, revealing widespread 3'UTR length changes across cell types.