Tanmay Mitra

This study simulates Alzheimer's disease progression using a mathematical model of the Amyloid cascade hypothesis, showing that brain geometry and neural activity influence amyloid plaque formation and neural atrophy.

This study develops a mathematical model showing that sleep disruption affects amyloid β fibrillization, suggesting that poor sleep hygiene may increase Alzheimer's disease risk by altering the balance between soluble and fibrillar amyloid β.