Cell BiologyNeurobiology of DiseasePeer-reviewed
Extracellular tau clearance is governed by its aggregation state and independent of microglial activation by LPS and IFN-γ
Andrew Shultz, Anna Vincze, Todd T. Yau…·Jennifer N. Rauch
This study shows that human iPSC-derived microglia internalize and clear tau differently based on its aggregation state, and that acute inflammation does not affect tau clearance.
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