Matthias Le Bec

This paper introduces RSpFAST, a non-covalent chemogenetic platform for fluorescence imaging, and demonstrates its dual behavior as a stable label and a reversible photoswitcher.

The paper uses optogenetic tools to control pheromone gradients in budding yeast, enabling spatial regulation of mating behavior and cell fusion.

This paper uses optogenetics to control cooperation and cheating in yeast populations, showing that cooperation is most effective when cooperator domain size is constrained between two length-scales.

This study shows that yeast cell proliferation, survival, and signaling under periodic osmotic stress depend on the phasing of stress with glucose deprivation, highlighting the role of metabolic fluctuations in stress responses.

This study controls beta-carotene production in yeast using optogenetics across different lab-scale devices and finds that illumination, culture volume, and shaking affect performance differently.