Yuanyuan Liu

This study shows that early postnatal CA3 hyperexcitability drives hippocampal development and epileptogenesis in SCN2A-DEE, suggesting it as a therapeutic target.

This study characterizes the biophysical and neurophysiological effects of the SCN8A p.(Gly1625Arg) mutation, showing a complex mix of gain-and loss-of-function properties leading to reduced neuronal firing.

This paper develops a method to label and image AIS proteins in living neurons using unnatural amino acids and bioorthogonal click chemistry, demonstrating its application to study NaV1.6 variants.