Author

Antonia A. Dominguez

Stanford UniversityORCID 0000-0002-4277-3445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:perturbation response prediction· 2 Assay:CRISPR screen· 1 Organism:human· 1

Frequent Co-Authors

Lei S. QiiD· 2 shared Haifeng WangiD· 1 shared Jan Marcel SkotheimiD· 1 shared Louai LabaniehiD· 1 shared Marius WernigiD· 1 shared Nathan H. KipnissiD· 1 shared P.C. Dave P. DingaliD· 1 shared S. Ali ShariatiiD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Lei S. QiORCID

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2 papers

Recent·Most cited

Molecular BiologyMolecular CellPeer-reviewedMay 1, 2019

Reversible disruption of specific transcription factor-DNA interactions using CRISPR/Cas9

S. Ali Shariati, Antonia A. Dominguez, Shicong Xie…·Jan Marcel Skotheim

This study develops a CRISPR/Cas9 method to reversibly disrupt specific transcription factor-DNA interactions and assess their functional impact on gene expression and cell division.

63 citations

experimental assayperturbation response prediction

𝕏 PostBluesky

Synthetic BiologyNature CommunicationsPeer-reviewedDec 14, 2017

Engineering Cell Sensing and Responses Using a GPCR-Coupled CRISPR-Cas System

Nathan H. Kipniss, P.C. Dave P. Dingal, Timothy R. Abbott…·Lei S. Qi

This paper introduces CRISPR ChaCha, a GPCR-Coupled CRISPR-Cas system that converts extracellular signals into genetic programs, showing improved performance over existing systems.

113 citationstop 4%

humanCRISPR screen

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