Yichi Niu

This study uses SAC-seq to map m6A modifications at single-nucleotide resolution in bovine preimplantation embryos, identifying a critical m6A site in RPL12 that regulates translation and development.

The paper introduces snapTotal-seq, a single-cell RNA-seq method that measures both nascent and mature RNA, and identifies regulatory hubs in cell cycle and senescence using LASSO regression.

This paper introduces a new single-cell WGA method to detect DNA damage-associated variants and finds that dSNV abundance is linked to genome topological compartments.