NeurosciencebioRxivPreprint
Isoflurane and surgery aggravate APOE4-dependent lipid dysregulation and neural dysfunction, leading to neurological impairment in male mice
Yun Li, Yuanyuan Ji, Çoşar Uzun…·Junfang Wu
This study shows that isoflurane anesthesia and surgery worsen lipid dysregulation and neural dysfunction in APOE4 mice, leading to neurological impairments.
DOI 10.64898/2026.07.31.742028