Author

Zheng Ruan

Department of Structural Biology, Van Andel InstituteORCID 0000-0002-4412-4916Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:protein sequence· 2 Research Focus:benchmarking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Natarajan KannaniD· 2 shared Wei LüiD· 2 shared Andrew R Jones· 1 shared Claire E EyersiD· 1 shared Dominic P Byrne· 1 shared Gemma Hardman· 1 shared Juan DuiD· 1 shared Junuk LeeiD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBioinformatics

Natarajan KannanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticseLifePeer-reviewedMay 18, 2026

Identification and classification of ion-channels across the tree of life provide functional insights into understudied CALHM channels

Rahil Taujale, Sung Jin Park, Nathan Gravel…·Natarajan Kannan

The paper identifies and classifies ion channels across species, revealing functional insights into understudied CALHM channels through sequence, structure, and functional data integration.

1 citation

humanmultiple species

𝕏 PostBluesky

BiochemistrybioRxivSep 10, 2023

Human Pannexin 1 Channel is NOT Phosphorylated by Src Tyrosine Kinase at Tyr199 and Tyr309

Zheng Ruan, Junuk Lee, Yangyang Li…·Wei Lü

This study shows that commercially available antibodies for detecting PANX1 tyrosine phosphorylation are nonspecific and that Src does not phosphorylate these sites in heterologous systems.

DOI 10.7554/elife.95118

humanprotein sequence

𝕏 PostBluesky

BiochemistrybioRxivPreprintOct 13, 2017

Extensive non-canonical phosphorylation in human cells revealed using strong-anion exchange-mediated phosphoproteomics

Gemma Hardman, Simon Perkins, Zheng Ruan…·Claire E Eyers

This study identifies extensive non-canonical phosphorylation in human cells using a new phosphoproteomics method, revealing over 1000 phospholysine sites and 310 phosphohistidine sites.

DOI 10.1101/202820

humanproteomics

𝕏 PostBluesky