Eleanor R. Gaunt

The paper identifies conserved overlapping accessory ORFs in coronavirus N genes and shows that nucleotide and codon biases drive their formation.

This study identifies cis-acting elements that regulate splicing balance between influenza A virus segment 7 mRNA1 and mRNA2, revealing key sequences that influence M1 and M2 protein expression.

This study investigates the evolutionary flexibility of influenza A virus splicing by testing mutations in SD and SA sites, finding that small changes can activate alternative splicing and produce viable variants with altered ion channel and M1 proteins.

The paper identifies missplicing as a common issue in heterologous gene expression and develops a splice-aware optimization algorithm to improve transgene performance.

This study identifies a virulence mechanism in low pathogenic avian influenza viruses where neuraminidase recruits plasminogen to cleave hemagglutinin, enhancing pathogenicity.

The study shows cow mammary gland cells can support replication of multiple IAV strains and are susceptible to co-infection with human and avian IAVs, suggesting the udder may act as a site for viral reassortment.

This study identifies compensatory mutations that cause replication defects in a CpG-enriched influenza A virus, revealing polymerase slippage and type I interferon induction as key mechanisms.

This study shows TRIM25 inhibits Influenza A virus by destabilizing its mRNA and is not required for the RIG-I pathway.