Cancer BiologyScientific DataPeer-reviewed
Homologous recombination deficiency in cell line libraries does not correlate with in vitro sensitivity to platinum agents or PARP inhibitors
Shiro Takamatsu, Kosuke Murakami, Noriomi Matsumura
This study finds that homologous recombination deficiency (HRD) in cancer cell lines is not associated with sensitivity to platinum agents or PARP inhibitors, contradicting clinical expectations.
16 citations