Author

Jenna E. Moyer

Weill Cornell MedicineORCID 0000-0002-4599-2969Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

Andrea SboneriD· 3 shared Juan Miguel MosqueraiD· 3 shared Jyothi ManohariD· 3 shared Michael SigourosiD· 3 shared Olivier ElementoiD· 3 shared Adriana IrizarryiD· 2 shared Ana M. MolinaiD· 2 shared Bishoy M. FaltasiD· 2 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Andrea SbonerORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintApr 10, 2025

Pan-Cancer PDOs Preserve Tumor Heterogeneity and Uncover Therapeutic Vulnerabilities

Hui–Hsuan Kuo, Bhavneet Bhinder, Hamza Numan Gokozan…·M. Laura Martín

This study develops a pan-cancer PDO platform to preserve tumor heterogeneity and identify therapeutic vulnerabilities, finding that 58% of PDOs respond to Talazoparib and combination screens reveal resistance-overcoming drugs.

DOI 10.1101/2025.04.10.647635

humanbulk RNA-seq

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Cancer BiologyCancer ResearchPeer-reviewedFeb 1, 2025

Kinome focused CRISPR-Cas9 screens in African ancestry patient-derived breast cancer organoids identifies essential kinases and synergy of EGFR and FGFR1 inhibition.

Florencia P. Madorsky Rowdo, Rachel N. Martini, Sarah E. Ackermann…·M. Laura Martín

The paper uses CRISPR-Cas9 screens in breast cancer organoids from African ancestry patients to identify essential kinases and show synergy between EGFR and FGFR1 inhibitors.

23 citationstop 3%

humanorganoid / primary culture

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GenomicsbioRxivPreprintMay 7, 2023

The Interplay between Mutagenesis and Extrachromosomal DNA Shapes Urothelial Cancer Evolution

Duy D. Nguyen, William F. Hooper, Timothy R. Chu…·Bishoy M. Faltas

This study examines how mutagenesis and extrachromosomal DNA contribute to urothelial cancer evolution, revealing clonal APOBEC3 mutations and chemotherapy-induced mutational bursts within ecDNA.

2 citations

humanwhole-genome sequencing

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