Larger inducible reservoir and higher abundance of exhausted CD8+ T cells in people treated after late versus non-late diagnosis of chronic HIV one year after ART initiation
Kathryn S. Hensley, Liset de Vries, Tanvir Hossain…·Tokameh Mahmoudi
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Erasmus MCORCID 0000-0002-4654-7509Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Kathryn S. Hensley, Liset de Vries, Tanvir Hossain…·Tokameh Mahmoudi
Sanne Reijm, Ana M. Marques, Jasper Rip…·Marvin M. van Luijn
The paper examines how HLA-B7 and HLA-A2 alleles influence EBV-specific CD8+ T cell effector phenotypes and their association with MS, finding HLA-B7-restricted cells are more exhausted and CNS-resident in MS patients.
Kou Hioki, Marlous Wildemans, Youkyung Lim…·Peter D. Katsikis
This study demonstrates that Prime-Target neoantigen vaccination effectively overcomes immunosuppression in 'cold' tumors by enhancing T cell infiltration and reshaping the tumor microenvironment.
Mateusz Stoszko, Abdullah M. S. Al‐Hatmi, Anton Škríba…·Tokameh Mahmoudi
The paper identifies gliotoxin as a novel LRA that disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency in CD4+ T cells.