Dennis Botman

The paper systematically compares novel fluorescent proteins in budding yeast to evaluate their characteristics for research applications.

The paper develops a glucose biosensor, TINGL, for measuring intracellular glucose dynamics in yeast and human cells, showing it detects glucose concentrations up to 1 mM and responds to glucose addition in starved cells.

This study investigates how budding yeast adapts to sucrose transitions by analyzing cAMP signaling dynamics and their impact on growth and metabolism.

The paper develops a pH-insensitive ATP biosensor for yeast and shows single-cell heterogeneity in ATP dynamics during nutrient transitions.

The paper characterizes 27 fluorescent proteins in vivo in yeast, finding differences from in vitro data and showing how codon optimization affects their properties.