Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome-wide association study in over 12,000 non-demented participants
Vincent Damotte, Sven J. van der Lee, Vincent Antoine Chouraki…·Cornelia M. van Duijn
Author
InsermORCID 0000-0002-4698-1794Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Vincent Damotte, Sven J. van der Lee, Vincent Antoine Chouraki…·Cornelia M. van Duijn
Adam Christian Naj, Ganna Leonenko, Xueqiu Jian…·Gerard D. Schellenberg
Verneri Anttila, Brendan K Bulik-Sullivan, Hilary K. Finucane…·Nicholas A. Furlotte
Genetic correlations across 25 brain disorders (215,683 cases) reveal broad psychiatric common-variant sharing, largely distinct neurological disorders, and migraine as the only significant cross-category link.
B K Kunkle, Benjamin Grenier‐Boley, Rebecca Sims…·Clive Holmes
This study performs a large GWAS of Alzheimer's disease, identifies four new risk loci, and highlights pathways involving immunity, lipid metabolism, and APP/Aβ processing.
The International Genomics of Alzheimer's Project, Kuan-lin Huang, The Alzheimer's Disease Neuroimaging Initiative…·Alison Goate
This study identifies a haplotype lowering PU.1 expression in myeloid cells that delays Alzheimer’s disease onset by affecting gene expression and function.