Author
Scripps Research InstituteORCID 0000-0002-4701-1087Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Yi-Zong Lee, Yi-Nan Zhang, Maddy L. Newby…·Jiang Zhu
This study rationally designs and characterizes filovirus glycoproteins and nanoparticles in vitro and in vivo to aid vaccine development.
Yi-Zong Lee, Jerome Han, Yi-Nan Zhang…·Jiang Zhu
The study analyzes metastability in fusion proteins of RSV and hMPV to design stable uncleaved prefusion-closed trimers for vaccine development.
Yi-Nan Zhang, Keegan Braz Gomes, Yi-Zong Lee…·Jiang Zhu
This paper develops a single-component self-assembling nanoparticle vaccine targeting conserved M2e domains from both influenza A and B viruses, showing 100% protection against H1N1 and 70% against Yamagata lineage influenza B in mice.