Jaakko S. Tyrmi

This study identifies maternal and fetal genetic contributions to preeclampsia through genome-wide association analyses, revealing distinct genetic architectures and biological pathways.

This study evaluates species-specific c0t-1 DNA blockers for exome capture in Pinus sylvestris, showing improved performance over universal blockers.

This study identifies 31 plasma proteins and expands genetic loci associated with PCOS, highlighting metabolic and hormonal influences and polygenic risk effects on cardio-metabolic outcomes.

This study identifies genetic loci associated with PCOS and shows genetic correlations with inflammation and sex hormones, improving PCOS prediction through polygenic risk scores.

The paper identifies five genetic loci associated with postpartum hemorrhage through a meta-analysis and links them to progesterone receptor binding sites and related traits.

This study conducts a GWAS of preeclampsia and hypertensive disorders of pregnancy, identifying 18 genome-wide significant loci, including novel associations with blood pressure and placental function.

The paper develops a 50K SNP genotyping array for Scots pine to enable genome-wide analyses and improve genetic research and breeding programs.

This study identifies three novel low-frequency variants associated with PCOS using a Finnish-Estonian GWAS, highlighting the value of population-specific genetic analysis.

This study identifies 36 novel genetic loci associated with uterine leiomyomata and suggests a causal link between genetic predisposition to increased fat-free mass and UL risk.

This study identifies coding loci and a large inversion associated with local adaptation in Pinus sylvestris using landscape genomics and targeted sequencing.

STAPLER simplifies creating, managing, and parallelizing bioinformatics workflows with user-friendly tools and modular customization.