Kay Grünewald

View Tomo improves cryoET by enabling 3D analysis and targeting through low-dose, rapid tomogram acquisition and automated processing.

This study uses electron cryo tomography to reveal the stepwise assembly of SPP1 phage particles from membrane-associated precursors within a viral DNA compartment in infected bacteria.

This study identifies genomic regions that become decompacted during adenovirus maturation, revealing how DNA sequence features guide genome organization for transcription.

This study visualizes F-actin in Plasmodium falciparum using electron cryo-tomography, revealing its structure and dynamics during gliding and its presence in the nucleus.

This study investigates the developmental program and functional properties of axon-carrying-dendrite neurons, revealing unique features of their axon initial segment.

The paper presents cryo-EM structures of SFTSV L protein during cap-snatching and transcription, revealing conformational changes and RNA binding mechanisms.

The paper identifies the palisade layer of the vaccinia virus core as composed of flexible A10 trimers using cryoET, STA, and AlphaFold2.

The paper introduces a pipeline combining AlphaFold2 and XL-MS to model protein conformations, showing improved accuracy in identifying correct structures using new scores.

The paper determines the cryo-EM structures of two amphibian antimicrobial peptides, revealing cross-β amyloid fibrils and their structural polymorphism.

This study uses consensus clustering of HSV1 protein interaction networks to uncover evolutionary links between herpesviruses and bacteriophages, identifying pUS10 as a potential evolutionary vestige.