Author

Shoin Tei

Institute for Quantitative Biosciences, The University of TokyoORCID 0000-0002-4868-8030Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Atsunori YoshimuraiD· 2 shared Katsuhiko ShirahigeiD· 2 shared Masashige BandoiD· 2 shared Masato T. KanemakiiD· 2 shared Toyoaki NatsumeiD· 2 shared Toyonori Sakata· 2 shared Takashi SutaniiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Atsunori YoshimuraORCID

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2 papers

Recent·Most cited

Molecular BiologyNature CommunicationsPeer-reviewedAug 24, 2026

Cohesin acts as a transcriptional gatekeeper by restraining pause-release to promote processive elongation

Shoin Tei, Masashige Bando, Toyonori Sakata…·Katsuhiko Shirahige

This study shows cohesin regulates multiple transcription steps, with loss leading to reduced induction but minimal steady-state expression changes.

4 citationstop 5%

statistical model

𝕏 PostBluesky

Molecular BiologybioRxivPreprintMar 15, 2024

Cohesin regulates promoter-proximal pausing of RNA Polymerase II by limiting recruitment of super elongation complex

Shoin Tei, Toyonori Sakata, Atsunori Yoshimura…·Katsuhiko Shirahige

This study shows cohesin limits super elongation complex recruitment to promoters, thereby regulating RNA Polymerase II pausing and gene expression.

2 citations

humanbulk RNA-seq

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