Lili M. Blumenberg

BlackSheep identifies molecules aberrantly enriched in small sample cohorts using non-parametric differential extreme value analysis.

This study estimates the extent of post-translational proteasomal splicing in the immunopeptidome and finds it is lower than previously reported.

Hypercluster automates and accelerates unsupervised clustering by testing multiple models and hyperparameters in parallel, providing reproducible results.

The paper demonstrates a two-step mechanism of PRC2-mediated repressive domain formation through nucleation sites and long-range spreading of H3K27me2/3.