ImmunologyThe Journal of ImmunologyPeer-reviewed
Inferring B cell phylogenies from paired heavy and light chain BCR sequences with Dowser
Cole G. Jensen, Jacob Sumner, Steven H. Kleinstein, Kenneth B. Hoehn
This study evaluates methods for inferring B cell phylogenies using paired heavy and light chain BCR sequences, finding that incorporating light chains improves accuracy and that maximum likelihood methods with separate partitions are most reliable.