Johanna Geuder

The paper identifies and compares orthologous cell types across primate species using scRNA-seq data from embryoid bodies, finding limited transferability of marker genes between species.

CroCoNet quantitatively compares gene regulatory networks across species, identifying conserved and diverged modules, including POU5F1's rewired network in great apes.

The paper identifies glycogen metabolism differences in pluripotent cells across species that influence neural differentiation speed.

The paper investigates how pleiotropy affects the evolution of cis-regulatory elements, finding that more pleiotropic elements show greater conservation in function despite lower sequence conservation.

Prime-seq is a bulk RNA-seq method that is four-fold more cost-efficient than TruSeq while maintaining equivalent library complexity, measurement accuracy, and statistical power.

The paper introduces mcSCRB-seq, a new scRNA-seq protocol that improves sensitivity and efficiency through optimized experimental conditions.