Leif A. Kirsebom

The paper identifies the presence and expression of selenocysteine machinery genes in 40% of mycobacterial genomes and suggests regulatory roles for selC.

The paper shows that loss of ESX-1 genes in M. marinum strain 1218S increases transcription of ESX-6 and LOS genes, affecting colony morphology and biofilm formation.

The paper identifies temperature-resistant suppressor mutations in E. coli that compensate for the rnpA49 mutation in RNase P, revealing roles for Lon protease and RNase R in the mutant's degradation.

This study uses whole genome sequencing to reveal extensive genomic diversity among Mycobacterium marinum strains, suggesting they should be divided into two clusters.