Author

Roelof J.C. Kluin

The Netherlands Cancer InstituteORCID 0000-0002-5133-142XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea Del CortonaiD· 1 shared B. Franklin PughiD· 1 shared Chitvan Mittal· 1 shared Christel F. A. RamireziD· 1 shared Cor LieftinkiD· 1 shared Daan J. KloostermaniD· 1 shared Daniël de Groot· 1 shared Daniel TarantoiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Andrea Del CortonaORCID

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2 papers

Recent·Most cited

Cancer BiologyNature CommunicationsPeer-reviewedMar 22, 2024

Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma

Christel F. A. Ramirez, Daniel Taranto, Masami Ando‐Kuri…·Leila Akkari

This study identifies how cancer genetics shape the tumor microenvironment in hepatocellular carcinoma, revealing myeloid cell-specific vulnerabilities that can be targeted with GM-CSF inhibition.

44 citationstop 2%

mouseexperimental assay

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Molecular BiologyMolecular CellPeer-reviewedNov 22, 2023

A chromatin-associated regulator of RNA Polymerase III assembly at tRNA genes revealed by locus-specific proteomics

Maria Elize van Breugel, Ila van Kruijsbergen, Chitvan Mittal…·Fred van Leeuwen

The paper identifies Fpt1 as a chromatin-associated regulator that promotes RNA Polymerase III eviction from tRNA genes in response to nutrient changes in yeast.

7 citations

yeastproteomics

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