Author

Alexander J. Pfeil

University of North Carolina at Chapel HillORCID 0000-0002-5159-019XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Andrea M. GazzoiD· 1 shared Christopher A. Febres‐AldanaiD· 1 shared Elisa de StanchinaiD· 1 shared Inna KhodosiD· 1 shared Jenna-Marie DixiD· 1 shared Juan Luis Gomez MartiiD· 1 shared Kathryn Cecilia ArbouriD· 1 shared Leo GiliiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Andrea M. GazzoORCID

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1 paper

Recent·Most cited

Cancer BiologyClinical Cancer ResearchPeer-reviewedJan 16, 2026

RRAS and RRAS2 mutations are recurrent oncogenic drivers in lung cancer and are sensitive to the pan-RAS inhibitor RMC-6236

Alexander J. Pfeil, Tom Zhang, Ryan Cheng…·Romel Somwar

This study identifies RRASQ87L and RRAS2Q72L mutations as recurrent oncogenic drivers in lung cancer and shows sensitivity to the pan-RAS inhibitor RMC-6236.

3 citationstop 2%

humanwhole-exome sequencing

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